{"id":379,"date":"2016-12-15T11:13:16","date_gmt":"2016-12-15T09:13:16","guid":{"rendered":"http:\/\/rainerklement.com\/?page_id=379"},"modified":"2026-08-04T16:07:37","modified_gmt":"2026-08-04T14:07:37","slug":"review-articles","status":"publish","type":"page","link":"http:\/\/rainerklement.com\/en\/beispiel-seite\/publications\/review-articles","title":{"rendered":"Review articles"},"content":{"rendered":"<p><strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42546907\/\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #333399;\">25<\/span><\/a><span style=\"color: #333399;\">. <a href=\"https:\/\/authors.elsevier.com\/a\/1nYfCI6VH2oUi\" target=\"_blank\" rel=\"noopener\">Exome-matched protein as the ideal dietary amino acid pattern: A narrative review.<\/a><\/span> <br class=\"clear\"><\/strong><strong>Klement RJ. <\/strong><em>Progress in Biophysics and Molecular Biology<\/em>. 2026 Sep; 201:341-349. Download here: <a href=\"http:\/\/rainerklement.com\/wp-content\/uploads\/2026\/08\/Klement-2026-Exome-matched-protein-as-the-ideal-dietary-amino-acid-pattern.pdf\" target=\"_blank\" rel=\"noopener\">Exome-matched protein review<\/a><\/p>\n<p><strong><span style=\"color: #333399;\">24. <a style=\"color: #333399;\" href=\"https:\/\/www.imrpress.com\/journal\/IJVNR\/96\/3\/10.31083\/IJVNR48814\" target=\"_blank\" rel=\"noopener\">The &#8222;Novelty-as-Scarcity&#8220; hypothesis: An evolutionary hypothesis to describe a potential cause of global fattening<\/a><\/span>.<br class=\"clear\"><\/strong>Ben-Dor M, <strong>Klement RJ. <\/strong><em>International Journal for Vitamin and Nutrition Research<\/em>. 2026 June; 93(3):<span data-v-ae9dfafa=\"\">48814<\/span><\/p>\n<p><strong><span style=\"color: #800080;\"><span style=\"color: #000080;\">23.<\/span> <span style=\"color: #000080;\"><a style=\"color: #000080;\" href=\"https:\/\/bmcmedicine.biomedcentral.com\/articles\/10.1186\/s12916-024-03775-4\" target=\"_blank\" rel=\"noopener\">Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma.<\/a> <\/span><\/span><br class=\"clear\"><\/strong>Duraj T, Kalamian M, Zuccoli G, Marron JC, D&#8217;Agostino DP, Scheck AC, Poff A, Winter SF, Hu J, <strong>Klement RJ<\/strong>, Hickson A, Lee DC, Cooper I, Kofler B, Schwatz KA, Phillips MC, Champ CE, Zupec-Kania B, Tan-Shalaby J, Serfaty FM, Omene E, Arismendi-Morillo G, Kiebish M, Cheng R, El-Sakka AM, &#8230; Seyfried TN <em>BMC Medicine.<\/em> 2024 Dec; <span class=\"cit\">22(1):578<\/span><\/p>\n<p><strong><span style=\"color: #333399;\">22. Dose prescription for stereotactic body radiotherapy: general and organ specific consensus statement from the DEGRO\/DGMP Working Group Stereotactic Radiotherapy and Radiosurgery. <\/span><br class=\"clear\"><\/strong>Brunner TB, Boda-Heggemann J, B\u00fcrgy D, Corradini S, Dieckmann UK, Gawish A, Gerum S, Gkika E, Grohmann M, H\u00f6rner-Rieber J, Kirste S, <strong>Klement RJ<\/strong>, Moustakis C, Nestle U, Niyazi M, R\u00fchle A, Tanadini-Lang S, Winkler P, Zurl B, Wittig-Sauerwein A, Blanck O. <em>Strahlentherapie und Onkologie.<\/em> 2024 July;&nbsp;<span class=\"cit\">200(9):737-750<\/span><\/p>\n<p><strong><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S258979182400001X\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #333399;\">21. Cancer as a global health crisis with deep evolutionary roots.<\/span><\/a><br class=\"clear\"><\/strong><strong>Klement RJ<\/strong>. <em>Global Transitions<\/em>. 2024 Jan;<span class=\"cit\"> 6:45-46<br \/>\n<\/span><\/p>\n<p><strong><span style=\"color: #333399;\">20. <a style=\"color: #333399;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37261610\/\" target=\"_blank\" rel=\"noopener\">Metabolic factors associated with the prognosis of oligometastatic patients treated with stereotactic body radiotherapy<\/a>.<\/span><br class=\"clear\"><\/strong><strong>Klement RJ<\/strong>, Sweeney RA. <em>Cancer and Metastasis Reviews<\/em>. 2023 Sept;<span class=\"cit\"> 42(3):927-940<br \/>\n<\/span><\/p>\n<p><strong><span style=\"color: #333399;\">19. <a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fimmu.2021.655739\/abstract\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #000080;\">Vitamin D resistance as a possible cause of autoimmune diseases: A hypothesis confirmed by a therapeutic high-dose vitamin D protocol.<\/span><\/a><\/span><br class=\"clear\"><\/strong>Lemke B, <strong>Klement RJ<\/strong>, Schweiger F, Schweiger B, Spitz J. <em>Frontiers in Immunology<\/em>. 2021 Apr; <span class=\"cit\">12:655739<\/span><\/p>\n<p><strong><a href=\"https:\/\/link.springer.com\/article\/10.1007\/s12032-020-1337-2\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #333399;\">18. Ketogenic Diets in Medical Oncology: A Systematic Review with Focus on Clinical Outcomes<\/span><\/a>. <br class=\"clear\"><\/strong><strong>Klement RJ<\/strong>, Brehm N, Sweeney RA. <em>Medical Oncology<\/em>. 2020 Feb; 37(2):14. Download: <a href=\"http:\/\/rainerklement.com\/wp-content\/uploads\/2020\/01\/Ketogenic-diets-in-medical-oncology-a-systematic-review-Klement-2020.pdf\">Ketogenic diets in medical oncology<\/a><\/p>\n<p><strong><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2225411018301743?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #333399;\">17. Wilhelm Br\u00fcnings&#8216; forgotten contribution to the metabolic treatment of cancer utilizing hypoglycemia and a very low carbohydrate (ketogenic) diet<\/span><\/a>. <br class=\"clear\"><\/strong><strong>Klement RJ<\/strong>. <em>Journal of Traditional and Complementary Medicine<\/em>. 2019 Jul; 9(3):192-200<\/p>\n<p><strong><span style=\"color: #333399;\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30974836\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #000080;\">16. Potential protective mechanisms of ketone bodies in migraine prevention<\/span><\/a>.<\/span> <br class=\"clear\"><\/strong>Gross EC,<strong> Klement RJ<\/strong>, Schoenen J, D&#8217;Agostino DP, Fischer D. <em><span title=\"Current Opinion in Clinical Nutrition and Metabolic Care\">Nutrients<\/span><\/em>. 2019 Apr; 11(4):E811<\/p>\n<p><strong><a href=\"http:\/\/www.tandfonline.com\/doi\/abs\/10.1080\/09553002.2017.1380330\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #333399;\">15. The influence of ketogenic therapy on the 5 R\u2019s of radiobiology<\/span><\/a>. <br class=\"clear\"><\/strong><strong>Klement RJ<\/strong>. <em>International Journal of Radiation Biology. <\/em>2019 Apr; 95 (4):394-407. Download: <a href=\"http:\/\/rainerklement.com\/wp-content\/uploads\/2016\/12\/The-influence-of-ketogenic-therapy-on-the-5-R-s-of-radiobiology-Klement-2017.pdf\">The influence of ketogenic therapy on radiobiology<\/a><\/p>\n<p><strong><a href=\"https:\/\/www.mdpi.com\/1010-660X\/55\/4\/84\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #000080;\">14. Impact of different types of diet on gut microbiota profiles and cancer prevention and treatment<\/span><\/a>. <br class=\"clear\"><\/strong><strong>Klement RJ<\/strong>, Pazienza V. <em><span title=\"Current Opinion in Clinical Nutrition and Metabolic Care\">Medicina<\/span><\/em>. 2019 Mar; 55(4):84<\/p>\n<p><span style=\"color: #333399;\"><strong><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30531479\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #0000ff;\"><span style=\"color: #000080;\">13. The emerging role of ketogenic diets in cancer treatment<\/span><\/span><\/a>. <br class=\"clear\"><\/strong><\/span><strong>Klement RJ<\/strong>. <em><span title=\"Current Opinion in Clinical Nutrition and Metabolic Care\">Current Opinion in Clinical Nutrition and Metabolic Car<\/span>e<\/em>. 2019 Mar; 22(2):129-134<\/p>\n<p><strong><span style=\"color: #000080;\"><a style=\"color: #000080;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29130953\" target=\"_blank\" rel=\"noopener noreferrer\">12. Fasting, fats and physics: Combining ketogenic and radiation therapy against cancer<\/a>. <br class=\"clear\"><\/span><\/strong><strong>Klement RJ<\/strong>. <em>Complementary Medicine Research<\/em>. 2018 Apr; 25(2):102-113<\/p>\n<p><a href=\"https:\/\/f1000research.com\/articles\/6-1787\/v2\" target=\"_blank\" rel=\"noopener noreferrer\"><strong><span id=\"OLK_SRC_BODY_SECTION\" style=\"color: #000080;\">11. The sedentary (r)evolution: Have we lost our metabolic flexibility? <\/span><\/strong><\/a> <br class=\"clear\"><span id=\"OLK_SRC_BODY_SECTION\">Freese J, <strong>Klement RJ<\/strong>, Ruiz-N\u00fa\u00f1ez B, Schwarz S and L\u00f6tzerich H. <em>F1000 Research<\/em>. 2017 Oct; 6:1787 <\/span><\/p>\n<p><span style=\"color: #800000;\"><strong><span style=\"color: #993300;\"><a style=\"color: #993300;\" href=\"https:\/\/link.springer.com\/article\/10.1007\/s12032-017-0991-5\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #000080;\">10. Beneficial Effects of Ketogenic Diets for Cancer Patients &#8211; A Realist Review with Focus on Evidence and Confirmation<\/span><\/a><\/span>. <br class=\"clear\"><\/strong><\/span><strong>Klement RJ<\/strong>. <em>Medical Oncology. <\/em>2017 June; 34(8):132. Download: <a href=\"http:\/\/rainerklement.com\/wp-content\/uploads\/2016\/12\/Beneficial-effects-of-ketogenic-diets-for-cancer-patients-Klement-2017.pdf\">Beneficial effects of KDs for cancer patients (Klement 2017).<\/a>&nbsp; See also these <a href=\"http:\/\/rainerklement.com\/?p=542\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #000080;\">comments by Prasanta Bandyopadhyay<\/span><\/a>.<\/p>\n<p><span style=\"color: #993300;\"><strong><a style=\"color: #993300;\" href=\"https:\/\/www.thieme-connect.de\/products\/ejournals\/abstract\/10.1055\/s-0042-119739\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #000080;\">9. Die Pal\u00e4oern\u00e4hrung und ihr Stellenwert f\u00fcr die Pr\u00e4vention und Behandlung chronischer Krankheiten<\/span><\/a>. <br class=\"clear\"><\/strong><\/span>Lemke D, <strong>Klement RJ<\/strong>, Paul S, Spitz J. <em>Aktuelle Ern\u00e4hrungsmedizin. <\/em>2016 Dec; 41(6):437-449. Download: <a href=\"http:\/\/rainerklement.com\/wp-content\/uploads\/2016\/12\/Die_Pal\u00e4oern\u00e4hrung_AEM_2016.pdf\">Paleo_Review_AEM_2016<\/a><\/p>\n<p><span style=\"color: #993300;\"><strong><a style=\"color: #993300;\" href=\"http:\/\/jevohealth.com\/journal\/vol1\/iss1\/15\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #000080;\">8. An Evolutionary and Mechanistic Perspective on Dietary Carbohydrate Restriction in Cancer Prevention<\/span>.<\/a> <br class=\"clear\"><\/strong><\/span> Fine EJ, Champ CE, Feinman RD, M\u00e1rquez S,<strong> Klement RJ<\/strong>. <em>Journal of Evolution and Health. <\/em>2016 Sept; 1(1):15<\/p>\n<p><strong><span style=\"color: #993300;\"><a style=\"color: #993300;\" href=\"https:\/\/www.thieme-connect.de\/products\/ejournals\/abstract\/10.1055\/s-0042-102150\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #000080;\">7. Kann eine kohlenhydratarme\/ketogene Ern\u00e4hrung das Tumorwachstum verz\u00f6gern? (Can a low carbohydrate\/ketogenic diet retard tumor growth?)<\/span><\/a> <br class=\"clear\"><\/span> Klement RJ<\/strong>, K\u00e4mmerer U. <em>Aktuelle Ern\u00e4hrungsmedizin<\/em>. 2016 Apr; 41(2):95-102. Download: <a href=\"http:\/\/rainerklement.com\/wp-content\/uploads\/2016\/04\/Ketogene-Di\u00e4t-bei-Krebs-Aktuelle-Ern\u00e4hrungsmedizin-02-2016.pdf\">Ketogene-Di\u00e4t-bei-Krebs-Aktuelle-Ern\u00e4hrungsmedizin-02-2016.pdf<\/a><\/p>\n<p><strong><span style=\"color: #993300;\"><a style=\"color: #993300;\" href=\"http:\/\/www.hindawi.com\/journals\/pc\/2016\/9462975\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #000080;\">6. Fortifying the Treatment of Prostate Cancer with Physical Activity<\/span><\/a>. <br class=\"clear\"><\/span><\/strong>Champ CE, Francis L,<strong> Klement RJ, <\/strong>Dickerman R, Smith RP. <em>Prostate Cancer<\/em>. 2016 Feb; 2016:9462975<\/p>\n<p><strong><span style=\"color: #993300;\"><a style=\"color: #993300;\" href=\"http:\/\/www.nature.com\/oncsis\/journal\/v5\/n2\/full\/oncsis20162a.html\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #000080;\">5. Dietary and pharmacological modification of the insulin\/IGF-1 system: exploiting the full repertoire against cancer.<\/span><\/a> <br class=\"clear\"><\/span>Klement RJ<\/strong>, Fink M. <em>Oncogenesis<\/em>. 2016 Feb; 5:e193<\/p>\n<p><strong><span style=\"color: #993300;\"><a style=\"color: #993300;\" href=\"http:\/\/www.cancerbiomed.org\/index.php\/cocr\/article\/view\/648\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #000080;\">4. Restricting carbohydrates to fight head and neck cancer: Is this realistsic?<\/span><\/a> <br class=\"clear\"><\/span> Klement RJ.<\/strong>&nbsp;<em>Cancer Biology&nbsp;&amp; Medicine<\/em>. 2014 Sept; 11 (3):145-161<\/p>\n<p><span style=\"color: #993300;\"><a style=\"color: #993300;\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24436017\" target=\"_blank\" rel=\"noopener noreferrer\"><strong><span style=\"color: #000080;\">3. Calories, carbohydrates, and cancer therapy with radiation: exploiting the five R&#8217;s through dietary manipulation.<\/span><\/strong><\/a> <br class=\"clear\"><\/span><strong>Klement RJ<\/strong>, Champ CE. <em>Cancer and Metastasis Reviews<\/em>. 2014 Mar; 33 (14):217-229<\/p>\n<p><span style=\"color: #993300;\"><a style=\"color: #993300;\" href=\"http:\/\/www.nutritionandmetabolism.com\/content\/8\/1\/75\" target=\"_blank\" rel=\"noopener noreferrer\"><strong><span style=\"color: #000080;\">2. Is there a role for carbohydrate restriction in the treatment and prevention of cancer?<\/span><\/strong><\/a> <br class=\"clear\"><\/span> <strong>Klement RJ<\/strong>, K\u00e4mmerer U. <em>Nutrition &amp; Metabolism<\/em>. 2011 Oct; 8:75<\/p>\n<p><span style=\"color: #993300;\"><a style=\"color: #993300;\" href=\"http:\/\/adsabs.harvard.edu\/abs\/2010A%26ARv..18..567K\" target=\"_blank\" rel=\"noopener noreferrer\"><strong><span style=\"color: #000080;\">1. Halo streams in the solar neighbourhood.<\/span><\/strong><\/a> <br class=\"clear\"><\/span><strong>Klement RJ<\/strong>. <em>The Astronomy and Astrophysics Review<\/em>. 2010 Oct; 18 (4):567-594<\/p>","protected":false},"excerpt":{"rendered":"<p>25. Exome-matched protein as the ideal dietary amino acid pattern: A narrative review. Klement RJ. Progress in Biophysics and Molecular Biology. 2026 Sep; 201:341-349. Download here: Exome-matched protein review 24. The &#8222;Novelty-as-Scarcity&#8220; hypothesis: An evolutionary hypothesis to describe a potential cause of global fattening.Ben-Dor M, Klement RJ. International Journal for Vitamin and Nutrition Research. 2026 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":69,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0,"footnotes":""},"class_list":["post-379","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/rainerklement.com\/en\/wp-json\/wp\/v2\/pages\/379","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/rainerklement.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/rainerklement.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/rainerklement.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/rainerklement.com\/en\/wp-json\/wp\/v2\/comments?post=379"}],"version-history":[{"count":65,"href":"http:\/\/rainerklement.com\/en\/wp-json\/wp\/v2\/pages\/379\/revisions"}],"predecessor-version":[{"id":1742,"href":"http:\/\/rainerklement.com\/en\/wp-json\/wp\/v2\/pages\/379\/revisions\/1742"}],"up":[{"embeddable":true,"href":"http:\/\/rainerklement.com\/en\/wp-json\/wp\/v2\/pages\/69"}],"wp:attachment":[{"href":"http:\/\/rainerklement.com\/en\/wp-json\/wp\/v2\/media?parent=379"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}